Dr. Jim Dobies is the owner of South Point Pet Hospital in Belmont, NC, and over the last five years in practice has helped Ryder, Bella, and Hondo through numerous injuries and illnesses as they compete and hunt throughout the country. I have requested that he write an article on Exercise Induced Collapse (EIC) because it was found predominantly in the genetics of field bred Labrador Retrievers.
Exercise-Induced Collapse
James C. Dobies, DVM
Exercise-induced collapse (EIC) is the most common cause of collapse in young, healthy Labrador Retrievers. It is most commonly associated with field-trial dogs, but has been identified in other Labradors, Chesapeake Bay and Curly-Coated Retrievers, and Boykin Spaniels. Affected dogs are generally young (5 months to 3 years of age), extremely fit, and often have an excitable temperament.
EIC usually occurs after 5 to 20 minutes of strenuous exercise often accompanied by extreme excitement. The first sign may be a rocking or forced gait. The rear limbs become weak and wobbly. Sometimes this proceeds to an incoordinated gait. In severe episodes, the front limbs can become affected as well and the dogs may exhibit a complete inability to move. Some dogs with EIC suffer a loss of balance and fall over. Most dogs are conscious and alert during the episodes, but some will appear disoriented. Symptoms often worsen for up to 5 minutes even after exercise has ended.
It’s important for owners and handlers to immediately rest any dog showing signs of EIC because a few deaths have been reported. However, most dogs fully recover within 5 to 25 minutes with no permanent loss of function. The first time a dog collapses, it should be examined immediately by a veterinarian with knowledge of EIC to confirm the diagnosis. A dog previously diagnosed with EIC that does not recover from an episode of collapse within 30 minutes should be examined and treated by a veterinarian. Body temperature is frequently elevated in cases of EIC but it is no more severe than the elevated temperatures of unaffected dogs following exertion. It’s best to provide the same cooling therapies to all post-exercise dogs: access to shade or air conditioning; access to plenty of drinking water; wetting of the ears, paw pads, and coat with cool water; and allowing dogs to pant freely to self-regulate elevated body temperatures.
A dog with EIC should avoid the activities that bring on an episode. Some dogs have been successfully treated for EIC with phenobarbital, but this medication should only be prescribed and administered at the direction of licensed veterinarian. EIC is a hereditary condition and there is a DNA test to detect the EIC gene. Testing can be performed on blood, cheek swabs, dewclaws, and semen. The results are useful for owners in making decisions about the activities their dog can and cannot participate in, for breeders to assist in breeding decisions, and for veterinarians trying to diagnose dogs with potential neurological, neuromuscular or metabolic disorders.
References:
The website for the University of Minnesota Veterinary Diagnostic Laboratory: (http://www.vdl.umn.edu/ourservices/canineneuromuscular/home.html)
Harari, J. Exercise-induced collapse in Labrador retrievers: A comparison with unaffected dogs. Dvm360 August 1, 2009.
Hoskins, JD. Exercise-induced collapse in Labrador Retrievers. Dvm360 October 1, 2008.
Patterson, EE, Minor, KM, et al. A canine DNM1 mutation is highly associated with the syndrome of exercise-induced collapse. Nat Genet October 2008; 40 (10): 1235-9.




